Tetralogy of Fallot in a child with VACTERL association - A case report of uncommon occurrence

Main Article Content

Praveen Nagula, MD, DM Anjani Kiranmayi, MD, DM M. Vamsi Krishna, MD, DM Sambasiva Rao Ch., MD, DM Ravi Srinivas, MD, DM O. Adikesava Naidu, MD, DM, FACC, FESC, FSCAI KMK Reddy. P, MD, DM, FACC, FCSI, FESC


Tetralogy of Fallot (TOF) is the most common cause of cyanotic congenital heart disease in ventricular septal defect and pulmonary stenosis physiology. TOF is associated with many syndromes, the most common being Down Syndrome, Velocardiofacial syndrome, Holt Oram Syndrome, and Poland's syndrome. VACTERL association is rare in incidence compared to the above mentioned. 1 We report a case of TOF with the VACTERL association.

Article Details

How to Cite
NAGULA, Praveen et al. Tetralogy of Fallot in a child with VACTERL association - A case report of uncommon occurrence. Medical Research Archives, [S.l.], v. 8, n. 7, july 2020. ISSN 2375-1924. Available at: <https://journals.ke-i.org/mra/article/view/2171>. Date accessed: 04 aug. 2020. doi: https://doi.org/10.18103/mra.v8i7.2171.
Case Reports


1. Solomon BD. The etiology of VACTERL association: Current knowledge and hypotheses. Am J Med Genet C Semin Med Genet. 2018;178:440-6
2. Quan L, Smith DW. The VATER association. Vertebral defects, Anal atresia, T-E fistula with esophageal atresia, Radial and Renal dysplasia: a spectrum of associated defects. J Pediatr. 1973; 82(1):104-7.
3. Solomon BD. VACTERL / VATER Association. Orphanet J Rare Dis. 2011; 6:56.
4. Nora AH, Nora JJ. A syndrome of multiple congenital anomalies associated with teratogenic exposure. Arch Environ Health 1975;30:17-21.
5. Khoury MJ, Cordero JF, Greenberg F, James LM, Erickson JD. A population study of the VACTERL association: evidence for its etiologic heterogeneity. Pediatrics 1983; 71:815-20.
6. Cunningham BK, Hadley DW, Hannoush H, Meltzer AC, Niforatos N, Pineda Alvarez D, Sachdev V, Warren-Mora N, Solomon BD. Analysis of cardiac anomalies in the VACTERL association. Birth Defects Res A Clin Mol Teratol. 2013 Dec;97(12):792-7.
7. Weaver DD, Mapstone CL, Yu PL. The VATER Association. Analysis of 46 patients. Am J Dis Child 1986;140:225- 229.
8. Aguinaga M, Zenteno JC, Pérez-Cano H, Morán V: Sonic hedgehog mutation analysis in patients with VACTERL association. Am J Med Genet A. 2010; 152A: 781-783
9. Martinez-Frias ML, Frias JL, Opitz JM. Errors of morphogenesis and developmental field theory. Am J Med Genet. 1998; 76: 291-6.
10. Bressan MC, McDermott DA, Spencer RH, Basson CT. TBX5 genetic testing validates strict clinical criteria for HoltOram syndrome. Circulation 2003; 108: 358: A1675.

Most read articles by the same author(s)

Obs.: This plugin requires at least one statistics/report plugin to be enabled. If your statistics plugins provide more than one metric then please also select a main metric on the admin's site settings page and/or on the journal manager's settings pages.