‘The Thalamus: A Review of its Functional Anatomy’

Main Article Content

Rengin Kosif

Abstract

The diencephalon can be divided into four areas, which are interposed between the brain stem and cerebral hemispheres. The four subdivisions include the  hypothalamus to be discussed in a separate lecture, the ventral thalamus containing the subthalamic nucleus already discussed, the epithalamus which is made up mostly of the pineal body, and the dorsal thalamus (henceforth referred to as the thalamus). Anatomically, the dorsal thalamus subdivided in 50-60 nuclear groups. The focus of this review is its functional anatomy. In the spinal cord and brain stem portions of the course certain relay nuclei of the thalamus that transfer information from sub-cortical structures to the cerebral cortex. By virtue of these relay functions that encompass the major senses and motor systems, the thalamus is often referred to as the gateway to the cortex. The thalamus has numerous connections to other areas of the brain as well, and these are thought to be important in the integration of cerebral, cerebellar, and brainstem activity. Branches of the posterior cerebral artery supply much of the thalamus. Occlusion of these small branches results in a number of symptoms characteristic of the thalamic syndrome.

Article Details

How to Cite
KOSIF, Rengin. ‘The Thalamus: A Review of its Functional Anatomy’. Medical Research Archives, [S.l.], v. 4, n. 8, dec. 2016. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/740>. Date accessed: 16 apr. 2024.
Keywords
Thalamus, nuclei, functional anatomy
Section
Review Articles

References

REFERENCES
1. Herrero MT, Barcia C, Navarro JM. Functional Anatomy Of Thalamus And Basal Ganglia.Childs Nerv Syst. 2002 ;18(8):386-404.
2. M.T. Herrero, R. Insausti, C. Estrada. Thalamus: Anatomy. Brain Mapping: An Encyclopedic Reference,2015,pg:229–242,Volume2:Anatomy and Physiology, Systems. http://dx.doi.org/10.1016/B978-0-12-397025-1.00216-5
3. D.M. Katz, K. Chandar. Thalamus. Encyclopedia of the Neurological Sciences (Second Edition) (2014) , Pages 425–430.
4.Child ND, Benarroch EE. Anterior Nucleus Of The Thalamus: Functional Organization And Clinical Implications. Neurology. 2013 19;81(21):1869-76.
5. YD Van der Werf, MP Witter, HJ Groenewegen. The Intralaminar And Midline Nuclei Of The Thalamus. Anatomical And Functional Evidence For Participation in Processes Of Arousal And Awareness. Brain Research Reviews,39:2–3, 2002, 107–140.
6. M. Steriade, L.L. Glenn. Neocortical And Caudate Projections Of Intralaminar Thalamic Neurons And Their Synaptic Excitation From Midbrain Reticular Core. J. Neurophysiol., 48 (1982), pp. 352–371.
7. M. Steriade. Thalamic Substrates Of Disturbances İn States Of Vigilance And Consciousness in Humans. M. Steriade, E.G. Jones, D.A. McCormick (Eds.), Thalamus, Experimental and Clinical Aspects, Vol. II, , Elsevier, Amsterdam (1997), pp. 721–742.

8. W. Sturm, A. De Simone, B.J. Krause, K. Specht, V. Hesselmann, I. Radermacher, H. Herzog, L. Tellmann, H.W. Müller-Gärtner, K. Willmes.• Functional Anatomy Of Intrinsic Alertness: Evidence For A Fronto-Parietal-Thalamic-Brainstem Network İn The Right Hemisphere. Neuropsychologia, 37 (1999), pp. 797–805.

9. S. Kinomura, J. Larsson, B. Gulyás, PE Roland. Activation by Attention Of The Human Reticular Formation And Thalamic İntralaminar Nuclei.Science, 271 (1996), 512 – 515.

10. RS Swenson. Review of Clinical and Functional Neuroscience. Chapter 10 , Thalamic Organization. http://www.dartmouth.edu/%7Erswenson/NeuroSci/chapter_10.html.
11. NR. McFarland, S N. Haber. Thalamic Relay Nuclei of the Basal Ganglia Form Both Reciprocal and Nonreciprocal Cortical Connections, Linking Multiple Frontal Cortical Areas . The Journal of Neuroscience, 2002, 22(18): 8117-8132.
12. SJ Mizumori , JD Williams. Directionally selective mnemonic properties of neurons in the lateral dorsal nucleus of the thalamus of rats. The Journal of Neuroscience, 1993, 13(9): 4015-4028.
13. L. Deecke, D. W. F. Schwarz, J. M. Fredrickson. Nucleus ventroposterior inferior (VPI) as the vestibular thalamic relay in the rhesus monkey I. Field potential investigation. Experimental Brain Research. 1974, 20:1; 88–100.
14. Lam YW, Sherman SM. Different topography of the reticulothalmic inputs to first- and higher-order somatosensory thalamic relays revealed using photostimulation. J Neurophysiol. 2007, 98(5):2903-9.
15. http://www.neuroanatomy.wisc.edu/coursebook/thalamus.pdf
16. Hans-Otto Karnath, Leif Johannsen, Doris Broetz ,Wilhelm Küker. Posterior Thalamic Hemorrhage İnduces “Pusher Syndrome”. Neurology , 2005, 64: 6; 1014-1019.
17. NN Doron, JE Ledoux. Cells in the posterior thalamus project to both amygdala and temporal cortex: A quantitative retrograde double-labeling study in the rat. Journal of Comperative Neurology. 425: 2; 257–274, 2000.

18. SM Sherman, RW Guillery. Exploring the Thalamus and Its Role in Cortical Function, Second edition. 2nd edition. Chapter I. Cambridge, MA USA. https://mitpress.mit.edu/sites/default/files/titles/content/9780262513449_sch_0001.pdf.

19. Didier Pinault. The Thalamic Reticular Nucleus: Structure, Function And Concept. Brain Research Reviews. 46: 1, 2004, Pages 1–31.
20. Spinella M. Hypersexuality and Dysexecutive Syndrome After A Thalamic Infarct. Int J Neurosci. 2004 Dec;114(12):1581-90.