Massive tongue edema from an allergic reaction to an antibiotic: epinephrine may avert need for endotracheal intubation

Main Article Content

Won Chee


Massive tongue edema from allergic reaction to medications raises a serious concern for maintaining adequate respiration as well as establishing endotracheal intubation.  The necessity for airway intervention depends on the extent of airway edema, particularly the involvement to the laryngeal areas. Administration of subcutaneous epinephrine may rapidly decrease swelling of the tongue and may avert complications of airway intervention.

Article Details

How to Cite
CHEE, Won. Massive tongue edema from an allergic reaction to an antibiotic: epinephrine may avert need for endotracheal intubation. Medical Research Archives, [S.l.], n. 2, apr. 2015. ISSN 2375-1924. Available at: <>. Date accessed: 25 june 2018.
tongue edema; epinephrine, intubation
Case Reports


1. Jungling AS, Shangraw RE. Massive Airway Edema after Azathioprine. Anesthesiology. 2000;92(3):888

2. Pruet CW, Kornblut AD, Kaliner MA. Management of the airway in patients with angioedema. Laryngoscope.1983;93(6):749–755

3. Kahlon S, Lee C, Chirurgi R, Hassen GW. Angioneurotic Edema Associated with Haloperidol. Case Reports in Emergency Medicine. 2012, Article ID 725461

4. Kaufman M. Ace Inhibitor-related Angioedema: Are Your Patients at Risk? Pharmacy &Therapeutics. 2013 Mar 38(3):170-172

5. Ishoo E, Shah UK, Grillone GA, Stram JR, Fuleihan NS. Predicting airway risk in angioedema. Staging system based on presentation. Otolaryngology, Head and Neck Surgery. 1999; 121: 263–8

6. Sondhi D, Lippmann M, Murali G. Airway compromise due to angiotensin-converting enzyme inhibitor-induced angioedema: clinical experience at a large community teaching hospital. Chest. 2004 Aug;126(2):400-4

7. Bentsianov BL, Parhiscar A, Azer M, Gady H. The role of fibreoptic nasopharyngosopy in the management of the acute airway in angioneurotic oedema. Laryngoscope. 2000; 110: 2016–9

Most read articles by the same author(s)

Obs.: This plugin requires at least one statistics/report plugin to be enabled. If your statistics plugins provide more than one metric then please also select a main metric on the admin's site settings page and/or on the journal manager's settings pages.