Main Article Content
The cause of ischial sore is synovial bursa which is made of pressure or shear on the ischial bone. Because of this mechanism, ischial sore often has big subcutaneous pocket compared to its skin defect. To treat this ischial ulcer, complete pocket resection and reconstruction with appropriate flap is the popular way, but we could treat five relapsing ischial sores by applying PRP and direct closing. Ischial sores are often found on the buttock of paraplegia patients who keep sitting on wheel chairs long time. They have high possibility of recurrence of ischial sores as long as using wheel chairs. This method is useful for them because no normal tissues around sore is resected and possibility of using local flaps can be remained when sore relapse.
The Medical Research Archives grants authors the right to publish and reproduce the unrevised contribution in whole or in part at any time and in any form for any scholarly non-commercial purpose with the condition that all publications of the contribution include a full citation to the journal as published by the Medical Research Archives.
2) Homma K, Murakami G, Fujioka H, et al. Treatment of ischial pressure ulcers with a posteromedial thigh fasciocutaneous flap. Plast Reconstr Surg 2001;108:1990-6.
3) Lin H, Hou C, Chen A, et al. Long-term outcome of using posterior-thigh fasciocutaneous flaps for the treatment of ischial pressure sores. J Recontr Microsurg 2010;26:355-8.
4) Ahluwalia R, Martin D, Mahoney JL. The operative treatment of pressure wounds: a 10-year experience in flap selection. Int Wound J 2010;7:103-6.
5) Hayashi T. Treatment of ischial pressure sores by means of sclerothrapy using absolute ethanol. Ann Plast Surg 2004;53:554-9.
6) Ono T. Treatment of sacral pressure ulcer with giant pocket utilizing trafermin. Mie Med 2005;49:25-9.
7) Baynham SA, Kohlman P, Katner HP. Treating stage IV pressure ulcers with negative pressure therapy: a case report. Wound Manage 1999;45:28-32,34-5.
8) Marx RE, Carlson ER, Eichstaedt RM, et al. Platelet-rich plasma-growth factor enhancement for bone grafts. Oral Surg Oras Med Oral Pathol Oral Radiol Endod 1998;85:638-46.
9) Scott AS, Jeffery JE, Timothy WR, et al. A case report on the use of sustained release platelet-rich plasma for the treatment of chronic pressure ulcers. J Spinal Cord Med 2011;34:122-7.
10) Scimeca CL, Bharara M, Fisher TK, et al. Novel use of platelet-rich plasma to augment curative diabetic foot surgery. J Diabetes Sci Technol 2010;4:1121-6.
11) Ogawa Y, Sawamura SJ, Ksander GA, et al. Transforming growth factors-beta 1 and beta 2 induce synthesis and accumulation of hyaluronate and chondroitin sulfate in vivo. Growth Factors 1990;3:53-62.
12) Gonshor A. technique for producing platelet-rich plasma and platelet concentrate. Int J Periodontics Restorative Dent 2002;22:547-57.
13) Sandra SS, Mickael T, Enrico V. Nonactivated versus thrombin-activated platelets on wound healing and fibroblast to myofibroblast differentiation in vivo and in vitro. Plast Reconstr Surg 2012;129:46e-54e.