Double Balloon Enteroscopy: The Growing Indications and Experience

Main Article Content

George Nayana Raghavapuram Sai Seamus Murphy Tharian Ben



Article Details

How to Cite
NAYANA, George et al. Double Balloon Enteroscopy: The Growing Indications and Experience. Medical Research Archives, [S.l.], v. 5, n. 11, nov. 2017. ISSN 2375-1924. Available at: <>. Date accessed: 28 may 2018. doi:
Research Articles


1. Yamamoto H, Sekine Y, Sato Y, Higashizawa T, Miyata T, Iino S, et al. Total enteroscopy with a nonsurgical steerable double-balloon method. Gastrointest Endosc. 2001 Feb;53(2):216–20.
2. Kim J. Training in Endoscopy: Enteroscopy. Clin Endosc. 2017 Jul;50(4):328–33.
3. Despott EJ, Murino A, Fraser C. Management of deep looping when failing to progress at double-balloon enteroscopy. Endoscopy. 2011;43 Suppl 2 UCTN:E275-276.
4. Mehdizadeh S, Ross A, Gerson L, Leighton J, Chen A, Schembre D, et al. What is the learning curve associated with double-balloon enteroscopy? Technical details and early experience in 6 U.S. tertiary care centers. Gastrointest Endosc. 2006 Nov;64(5):740–50.
5. Tee H-P, How S-H, Kaffes AJ. Learning curve for double-balloon enteroscopy: Findings from an analysis of 282 procedures. World J Gastrointest Endosc. 2012 Aug 16;4(8):368–72.
6. Li X-B, Dai J, Chen H-M, Zhuang J, Song Y, Gao Y-J, et al. A novel modality for the estimation of the enteroscope insertion depth during double-balloon enteroscopy. Gastrointest Endosc. 2010 Nov;72(5):999–1005.
7. May A. Performing Double-Balloon Enteroscopy: The Utility of the Erlangen EndoTrainer. Tech Gastrointest Endosc. 2008 Apr;10(2):54–8.
8. Yamamoto H, Kita H, Sunada K, Hayashi Y, Sato H, Yano T, et al. Clinical outcomes of double-balloon endoscopy for the diagnosis and treatment of small-intestinal diseases. Clin Gastroenterol Hepatol Off Clin Pract J Am Gastroenterol Assoc. 2004 Nov;2(11):1010–6.
9. Gerson LB. Double-balloon enteroscopy: the new gold standard for small-bowel imaging? Gastrointest Endosc. 2005 Jul;62(1):71–5.
10. Yang D-H. Questions about sedation protocols for double-balloon enteroscopy. Intest Res. 2015 Jan;13(1):97–8.
11. Han S, Bhattacharya K, Cave DR. Preliminary colonoscopy facilitates retrograde double-balloon enteroscopy. Endosc Int Open. 2014 Dec;2(4):E241-243.
12. Sulbaran M, de Moura E, Bernardo W, Morais C, Oliveira J, Bustamante-Lopez L, et al. Overtube-assisted enteroscopy and capsule endoscopy for the diagnosis of small-bowel polyps and tumors: a systematic review and meta-analysis. Endosc Int Open. 2016 Feb;4(2):E151-163.
13. Di Caro S, May A, Heine DGN, Fini L, Landi B, Petruzziello L, et al. The European experience with double-balloon enteroscopy: indications, methodology, safety, and clinical impact. Gastrointest Endosc. 2005 Oct;62(4):545–50.
14. Rahman A, Ross A, Leighton JA, Schembre D, Gerson L, Lo SK, et al. Double-balloon enteroscopy in Crohn’s disease: findings and impact on management in a multicenter retrospective study. Gastrointest Endosc. 2015 Jul;82(1):102–7.
15. Peyrin-Biroulet L, Loftus EV, Colombel J-F, Sandborn WJ. The natural history of adult Crohn’s disease in population-based cohorts. Am J Gastroenterol. 2010 Feb;105(2):289–97.
16. Couckuyt H, Gevers AM, Coremans G, Hiele M, Rutgeerts P. Efficacy and safety of hydrostatic balloon dilatation of ileocolonic Crohn’s strictures: a prospective longterm analysis. Gut. 1995 Apr;36(4):577–80.
17. Reinisch W, Colombel J-F, D’Haens G, Sandborn WJ, Rutgeerts P, Geboes K, et al. Characterisation of Mucosal Healing with Adalimumab Treatment in Patients with Moderately to Severely Active Crohn’s Disease: Results from the EXTEND Trial. J Crohns Colitis. 2016 Oct 10;
18. Murphy SJ, Kornbluth A. Double balloon enteroscopy in Crohn’s disease: where are we now and where should we go? Inflamm Bowel Dis. 2011 Jan;17(1):485–90.
19. Ell C, May A. Mid-gastrointestinal bleeding: capsule endoscopy and push-and-pull enteroscopy give rise to a new medical term. Endoscopy. 2006 Jan;38(1):73–5.
20. May A, Friesing-Sosnik T, Manner H, Pohl J, Ell C. Long-term outcome after argon plasma coagulation of small-bowel lesions using double-balloon enteroscopy in patients with mid-gastrointestinal bleeding. Endoscopy. 2011 Sep;43(9):759–65.
21. Samaha E, Rahmi G, Landi B, Lorenceau-Savale C, Malamut G, Canard J-M, et al. Long-term outcome of patients treated with double balloon enteroscopy for small bowel vascular lesions. Am J Gastroenterol. 2012 Feb;107(2):240–6.
22. Shinozaki S, Yamamoto H, Yano T, Sunada K, Hayashi Y, Shinhata H, et al. Favorable long-term outcomes of repeat endotherapy for small-intestine vascular lesions by double-balloon endoscopy. Gastrointest Endosc. 2014 Jul;80(1):112–7.
23. Shimamura Y, Kandel G, May G. Deflating the Lure of Double-Balloon Enteroscopy. J Clin Gastroenterol. 2016 Sep;50(8):688–9.
24. Tomba C, Sidhu R, Sanders DS, Mooney PD, Branchi F, Locatelli M, et al. Celiac Disease and Double-Balloon Enteroscopy: What Can We Achieve?: The Experience of 2 European Tertiary Referral Centers. J Clin Gastroenterol. 2016 Apr;50(4):313–7.
25. Hadithi M, Al-toma A, Oudejans J, van Bodegraven AA, Mulder CJ, Jacobs M. The value of double-balloon enteroscopy in patients with refractory celiac disease. Am J Gastroenterol. 2007 May;102(5):987–96.
26. Cellier C, Cuillerier E, Patey-Mariaud de Serre N, Marteau P, Verkarre V, Brière J, et al. Push enteroscopy in celiac sprue and refractory sprue. Gastrointest Endosc. 1999 Nov;50(5):613–7.
27. Valitutti F, Di Nardo G, Barbato M, Aloi M, Celletti I, Trovato CM, et al. Mapping histologic patchiness of celiac disease by push enteroscopy. Gastrointest Endosc. 2014 Jan;79(1):95–100.
28. Weyenberg SJBV, Jarbandhan SVA, Mulder CJJ, Jacobs M a. JM. Double Balloon Endoscopy in Celiac Disease. Tech Gastrointest Endosc. 2008 Apr 1;10(2):87–93.
29. Tomba C, Sidhu R, Sanders DS, Mooney PD, Branchi F, Locatelli M, et al. Celiac Disease and Double-Balloon Enteroscopy: What Can We Achieve?: The Experience of 2 European Tertiary Referral Centers. J Clin Gastroenterol. 2016 Apr;50(4):313–7.
30. Fry LC, Bellutti M, Neumann H, Malfertheiner P, Monkemuller K. Utility of double-balloon enteroscopy for the evaluation of malabsorption. Dig Dis Basel Switz. 2008;26(2):134–9.
31. Cangemi DJ, Stark ME, Cangemi JR, Lukens FJ, Gómez V. Double-balloon enteroscopy and outcomes in patients older than 80. Age Ageing. 2015 May;44(3):529–32.
32. Robles EP-C, Delgado PE, Conesa PB, Andrés BM, Guggiana MF, Mateos EA, et al. Role of double-balloon enteroscopy in malignant small bowel tumors. World J Gastrointest Endosc. 2015 Jun 10;7(6):652–8.
33. Liu K, Joshi V, Saxena P, Kaffes AJ. Predictors of success for double balloon-assisted endoscopic retrograde cholangiopancreatography in patients with Roux-en-Y anastomosis. Dig Endosc Off J Jpn Gastroenterol Endosc Soc. 2017 Mar;29(2):190–7.
34. De Koning M, Moreels TG. Comparison of double-balloon and single-balloon enteroscope for therapeutic endoscopic retrograde cholangiography after Roux-en-Y small bowel surgery. BMC Gastroenterol. 2016 Aug 22;16(1):98.
35. Cheng C-L, Liu N-J, Tang J-H, Yu M-C, Tsui Y-N, Hsu F-Y, et al. Double-balloon enteroscopy for ERCP in patients with Billroth II anatomy: results of a large series of papillary large-balloon dilation for biliary stone removal. Endosc Int Open. 2015 Jun;3(3):E216-222.
36. Pinho R, Proença L, Alberto L, Carvalho J, Pinto-Pais T, Fernandes C, et al. Biliary self-expandable metallic stent using single balloon enteroscopy assisted ERCP--overcoming limitations of current accessories. Rev Espanola Enfermedades Dig Organo Of Soc Espanola Patol Dig. 2013 Oct;105(9):561–4.
37. Trindade AJ, Mella JM, Slattery E, Cohen J, Dickstein J, Garud SS, et al. Use of a cap in single-balloon enteroscopy-assisted endoscopic retrograde cholangiography. Endoscopy. 2015 May;47(5):453–6.
38. Tsutsumi K, Kato H, Okada H. Impact of a Newly Developed Short Double-Balloon Enteroscope on Stent Placement in Patients with Surgically Altered Anatomies. Gut Liver. 2017 Mar 15;11(2):306–11.
39. Kawamura T, Yasuda K, Tanaka K, Uno K, Ueda M, Sanada K, et al. Clinical evaluation of a newly developed single-balloon enteroscope. Gastrointest Endosc. 2008 Dec;68(6):1112–6.
40. Lipka S, Rabbanifard R, Kumar A, Brady P. Single versus double balloon enteroscopy for small bowel diagnostics: a systematic review and meta-analysis. J Clin Gastroenterol. 2015 Mar;49(3):177–84.
41. Akyuz U, Akyuz F. Diagnostic and Therapeutic Capability of Double-Balloon Enteroscopy in Clinical Practice. Clin Endosc. 2016 Mar;49(2):157–60.
42. Kameda N, Higuchi K, Shiba M, Machida H, Okazaki H, Yamagami H, et al. A prospective, single-blind trial comparing wireless capsule endoscopy and double-balloon enteroscopy in patients with obscure gastrointestinal bleeding. J Gastroenterol. 2008;43(6):434–40.
43. Wang J, Guo Q, Zhao J, Liu M, Liao G, Chen N, et al. Multidetector CT Enterography versus Double-Balloon Enteroscopy: Comparison of the Diagnostic Value for Patients with Suspected Small Bowel Diseases. Gastroenterol Res Pract. 2016;2016:5172873.
44. Goverde A, Korsse SE, Wagner A, van Leerdam ME, Krak NC, Stoker J, et al. Small-bowel Surveillance in Patients With Peutz-Jeghers Syndrome: Comparing Magnetic Resonance Enteroclysis and Double Balloon Enteroscopy. J Clin Gastroenterol. 2017 Apr;51(4):e27–33.
45. Seiderer J, Herrmann K, Diepolder H, Schoenberg SO, Wagner AC, Göke B, et al. Double-balloon enteroscopy versus magnetic resonance enteroclysis in diagnosing suspected small-bowel Crohn’s disease: Results of a pilot study. Scand J Gastroenterol. 2007 Jan 1;42(11):1376–85.
46. Mensink PBF, Haringsma J, Kucharzik T, Cellier C, Pérez-Cuadrado E, Mönkemüller K, et al. Complications of double balloon enteroscopy: a multicenter survey. Endoscopy. 2007 Jul;39(07):613–5.
47. Mensink PBF. Complications of Double Balloon Enteroscopy. Tech Gastrointest Endosc. 2008 Apr 1;10(2):66–9.
48. Möschler O, May A, Müller MK, Ell C, German DBE Study Group. Complications in and performance of double-balloon enteroscopy (DBE): results from a large prospective DBE database in Germany. Endoscopy. 2011 Jun;43(6):484–9.
49. Kopáčová M, Bureš J, Rejchrt S, Vávrová J, Bártová J, Soukup T, et al. Risk Factors of Acute Pancreatitis in Oral Double Balloon Enteroscopy. Acta Medica (Hradec Kralove). 2016;59(3):84–90.
50. Girelli CM, Pometta R, Facciotto C, Mella R, Bernasconi G. First report of splenic rupture following deep enteroscopy. World J Gastrointest Endosc. 2016 May 10;8(9):391–4.
51. Chen W-G, Shan G-D, Zhang H, Yang M, L L, Yue M, et al. Double-balloon enteroscopy in small bowel diseases: Eight years single-center experience in China. Medicine (Baltimore). 2016 Oct;95(42): e5104.
52. Neuhaus H, Beyna T, Schneider M, Devière J. Novel motorized spiral enteroscopy: first clinical case. VideoGIE. 1(2):32–3.
53. Ali R, Wild D, Shieh F, Diehl DL, Fischer M, Tamura W, et al. Deep enteroscopy with a conventional colonoscope: initial multicenter study by using a through-the-scope balloon catheter system. Gastrointest Endosc. 2015 Nov;82(5):855–60.
54. Gralnek IM, Suissa A, Domanov S. Safety and efficacy of a novel balloon colonoscope: a prospective cohort study. Endoscopy. 2014 Oct;46(10):883–7.
55. Moreels TG. Update in enteroscopy: New devices and new indications. Dig Endosc Off J Jpn Gastroenterol Endosc Soc. 2017 Jul 14;
56. Song LMWK, Baron TH, Saleem A, Bruining DH, Alexander JA, Rajan E. Double-balloon enteroscopy as a rescue technique for failed direct percutaneous endoscopic jejunostomy when using conventional push enteroscopy (with video). Gastrointest Endosc. 2012 Sep;76(3):675–9.
57. Yokoyama K, Yano T, Kumagai H, Mizuta K, Ono S, Imagawa T, et al. Double-balloon Enteroscopy for Pediatric Patients: Evaluation of Safety and Efficacy in 257 Cases. J Pediatr Gastroenterol Nutr. 2016 Jul;63(1):34–40.
58. Belsha D, Urs A, Attard T, Thomson M. Effectiveness of Double-balloon Enteroscopy-facilitated Polypectomy in Paediatric Patients With PEUTZ-Jeghers Syndrome. J Pediatr Gastroenterol Nutr. 2017 Mar 17;

Most read articles by the same author(s)

Obs.: This plugin requires at least one statistics/report plugin to be enabled. If your statistics plugins provide more than one metric then please also select a main metric on the admin's site settings page and/or on the journal manager's settings pages.