The role of dendritic cells in vertebrates: a review

Main Article Content

stefano bacci

Abstract

Dendritic cells are essential for the induction of adaptive immune responses. Their main function is to process antigen material and present it on the cell surface to the T cells of the immune system through a complex mechanism. Therefore, knowledge of this cell type is required to understand also the evolution of immune system in vertebrates. In fact from the amphioxus is possible to follow the evolution of these cells until the man where dendritic cells are present in myeloid and plasmacytoid lines. Besides recent studies define dendritic cells as an independent lineage of hematopoietic cells originating from a common precursor and distinct transcription factors, during the natural history, control the development of these cells until man. Using a comparative approach based on phenotype and function, this review attempts to give a key to classify DC in all classes of vertebrates.

Article Details

How to Cite
BACCI, stefano. The role of dendritic cells in vertebrates: a review. International Biology Review, [S.l.], v. 1, n. 1, may 2017. ISSN 2572-7168. Available at: <https://journals.ke-i.org/index.php/ibr/article/view/1266>. Date accessed: 24 june 2018. doi: https://doi.org/10.18103/ibr.v2i1.1266.
Keywords
medical, medicine,research,pharmacology
Section
Articles

Most read articles by the same author(s)

Obs.: This plugin requires at least one statistics/report plugin to be enabled. If your statistics plugins provide more than one metric then please also select a main metric on the admin's site settings page and/or on the journal manager's settings pages.