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Dr. Larry R. Masterson

Dr. Masterson is an Assistant Professor of Chemistry at Hamline University. He received his Lidoctoral degree in Chemistry in 2008 at the University of Minnesota. Since beginning his PhD, his work has led to over 20 publications, highlighted in journals such as Nature and the Proceedings of the National Academy of Science. This research mainly aimed at studies of protein-protein interactions in the context of heart muscle contractility, specifically those that are correlated with dilated cardiomyopathy. Dr. Masterson is now focused on understanding the mechanism behind protein dysfunction, leading to Alzheimer's disease or associated with Chronic Traumatic Encephalopathy from the head injuries of athletes. Using a battery of techniques, including thermal calorimetry, steady-state kinetics, Molecular Dynamics simulations, and NMR spectroscopy, Dr. Masterson is working to establish a general framework for the physical basis of protein aggregation. His long term goal is to establish a clearer understanding of the connection between protein structure, dynamics, and function, particularly in the context of disease.