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Low-molecular-weight heparins represent well-established agents for thromboprophylaxis in the orthopaedic and traumatological setting. The availability of different compounds requires the doctor to make a careful choice especially in the dose and duration of treatment, which represent two key factors for a successful therapy. In addition to the clinical benefit for the patient, an appropriate therapeutic choice allows the physician not to incur in medico-legal implications. In the present paper, we briefly review recent data from new trials in which nadroparin was used in patients after knee arthroscopy and lower leg plaster cast, and discuss the mode of use of the drug and the potential medico-legal implications.
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