Dendritic cells are essential for the induction of adaptive immune responses. Their main function is to process antigen material and present it on the cell surface to the T cells of the immune system through a complex mechanism. Therefore, knowledge of this cell type is required to understand also the evolution of immune system in vertebrates. In fact from the amphioxus is possible to follow the evolution of these cells until the man where dendritic cells are present in myeloid and plasmacytoid lines. Besides recent studies define dendritic cells as an independent lineage of hematopoietic cells originating from a common precursor and distinct transcription factors, during the natural history, control the development of these cells until man. Using a comparative approach based on phenotype and function, this review attempts to give a key to classify DC in all classes of vertebrates.
Authors will be required to fill out the below copyright transfer form during the peer-review process and attach it along with their submission. In return, Knowledge Enterprises Journals grants authors the right to publish and reproduce the unrevised contribution in whole or in part at any time and in any form for any scholarly non-commercial purpose with the condition that all publications of the contribution include a full citation to the journal as published by Knowledge Enterprises Journals.
Most read articles by the same author(s)
Obs.: This plugin requires at least one statistics/report plugin to be enabled. If your statistics plugins provide more than one metric then please also select a main metric on the admin's site settings page and/or on the journal manager's settings pages.
Copyright 2018. All rights reserved. Knowledge Enterprises Incorporated.